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Addition of mirror-image L-DNA elements to DNA amplification circuits to distinguish leakage from target signal

DNA amplification circuits that rely on thermodynamically-driven hybridization events triggered by a target nucleic acid are becoming increasingly utilized due to their relative simplicity. A drawback of these circuits is that non-specific amplification, or circuit leakage, must be estimated using a...

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Detalhes bibliográficos
Publicado no:Biosens Bioelectron
Main Authors: Zimmers, Zackary A., Adams, Nicholas M., Haselton, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202133/
https://ncbi.nlm.nih.gov/pubmed/34034212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2021.113354
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