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CRISPR-based targeting of DNA methylation in Arabidopsis thaliana by a bacterial CG-specific DNA methyltransferase

CRISPR-based targeted modification of epigenetic marks such as DNA cytosine methylation is an important strategy to regulate the expression of genes and their associated phenotypes. Although plants have DNA methylation in all sequence contexts (CG, CHG, CHH, where H = A, T, C), methylation in the sy...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ghoshal, Basudev, Picard, Colette L., Vong, Brandon, Feng, Suhua, Jacobsen, Steven E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201958/
https://ncbi.nlm.nih.gov/pubmed/34074795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2125016118
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