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CRISPR-based targeting of DNA methylation in Arabidopsis thaliana by a bacterial CG-specific DNA methyltransferase

CRISPR-based targeted modification of epigenetic marks such as DNA cytosine methylation is an important strategy to regulate the expression of genes and their associated phenotypes. Although plants have DNA methylation in all sequence contexts (CG, CHG, CHH, where H = A, T, C), methylation in the sy...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ghoshal, Basudev, Picard, Colette L., Vong, Brandon, Feng, Suhua, Jacobsen, Steven E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8201958/
https://ncbi.nlm.nih.gov/pubmed/34074795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2125016118
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