Intratumoral cancer chemotherapy with a carrier-based immunogenic cell death eliciting platinum (IV) agent

A carrier-based, immunogenic cell death (ICD)-eliciting platinum(IV) chemotherapeutic agent was synthesized via complexation between an axially derivatized Pt(IV)-tocopherol and hyaluronan-tocopherol nanocarrier. The resultant HA-Pt(IV) complex demonstrated anti-proliferative activity and induced ca...

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發表在:Mol Pharm
Main Authors: Groer, Chad, Zhang, Ti, Lu, Ruolin, Cai, Shuang, Mull, Derek, Huang, Aric, Forrest, Melanie, Berkland, Cory, Aires, Daniel, Forrest, Marcus Laird
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200829/
https://ncbi.nlm.nih.gov/pubmed/32975949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00781
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