Metabolomics Analysis Reveals Deranged Energy Metabolism and Amino Acid Metabolic Reprogramming in Dogs With Myxomatous Mitral Valve Disease

BACKGROUND: Myxomatous mitral valve disease (MMVD), a naturally occurring heart disease, affects 10% to 15% of the canine population. Canine MMVD shares many similarities with human MMVD. Untargeted metabolomics was performed to identify changes in metabolic pathways and biomarkers with potential cl...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Li, Qinghong, Larouche‐Lebel, Éva, Loughran, Kerry A., Huh, Terry P., Suchodolski, Jan S., Oyama, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200728/
https://ncbi.nlm.nih.gov/pubmed/33890477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018923
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