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New Oxaliplatin-Pyrophosphato Analogs with Improved In Vitro Cytotoxicity

Two new Pt(II)-pyrophosphato complexes containing the carrier ligands cis-1,3-diaminocyclohexane (cis-1,3-DACH) and trans-1,2-diamine-4-cyclohexene (1,2-DACHEX), variants of the 1R,2R-diaminocyclohexane ligand present in the clinically used Pt-drug oxaliplatin, have been synthesized with the aim of...

詳細記述

保存先:
書誌詳細
出版年:Molecules
主要な著者: Barbanente, Alessandra, Iacobazzi, Rosa Maria, Azzariti, Amalia, Hoeschele, James D., Denora, Nunzio, Papadia, Paride, Pacifico, Concetta, Natile, Giovanni, Margiotta, Nicola
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200237/
https://ncbi.nlm.nih.gov/pubmed/34200051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26113417
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