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Anti-Cancer Activities of Thyrointegrin α(v)β(3) Antagonist Mono- and Bis-Triazole Tetraiodothyroacetic Acid Conjugated via Polyethylene Glycols in Glioblastoma

SIMPLE SUMMARY: Different Triazole Tetrac (TAT) thyrointegrin αvβ3 antagonists exhibited optimal therapeutic efficacy against U87 or primary glioblastoma cells. TAT containing molecules bind with high affinity to the integrin αvβ3 and plasma protein Transthyretin (TTR), which facilitate transport ac...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Godugu, Kavitha, Rajabi, Mehdi, Mousa, Shaker A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8199894/
https://ncbi.nlm.nih.gov/pubmed/34204997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112780
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