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Anti-Inflammatory Effect of Auranofin on Palmitic Acid and LPS-Induced Inflammatory Response by Modulating TLR4 and NOX4-Mediated NF-κB Signaling Pathway in RAW264.7 Macrophages

Chronic inflammation, which is promoted by the production and secretion of inflammatory mediators and cytokines in activated macrophages, is responsible for the development of many diseases. Auranofin is a Food and Drug Administration-approved gold-based compound for the treatment of rheumatoid arth...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hwangbo, Hyun, Ji, Seon Yeong, Kim, Min Yeong, Kim, So Young, Lee, Hyesook, Kim, Gi-Young, Kim, Suhkmann, Cheong, JaeHun, Choi, Yung Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198732/
https://ncbi.nlm.nih.gov/pubmed/34072916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115920
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