Coralyne Radiosensitizes A549 Cells by Upregulation of CDKN1A Expression to Attenuate Radiation Induced G2/M Block of the Cell Cycle

Coralyne is a synthetic analog of berberine related to protoberberine-isoquinoline alkaloids. Isoquinoline derivatives and analogs are renowned as potent radiosensitizers with potential medical application. In the present study, we investigated the effect of coralyne on the cell death, cytoskeletal...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Węgierek-Ciuk, Aneta, Arabski, Michał, Ciepluch, Karol, Brzóska, Kamil, Lisowska, Halina, Czerwińska, Malwina, Stępkowski, Tomasz, Lis, Krzysztof, Lankoff, Anna
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198675/
https://ncbi.nlm.nih.gov/pubmed/34071406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115791
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