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Curcumin-Loaded Nanoparticles Impair the Pro-Tumor Activity of Acid-Stressed MSC in an In Vitro Model of Osteosarcoma

In the tumor microenvironment, mesenchymal stromal cells (MSCs) are key modulators of cancer cell behavior in response to several stimuli. Intratumoral acidosis is a metabolic trait of fast-growing tumors that can induce a pro-tumorigenic phenotype in MSCs through the activation of the NF-κB-mediate...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Di Pompo, Gemma, Cortini, Margherita, Palomba, Roberto, Di Francesco, Valentina, Bellotti, Elena, Decuzzi, Paolo, Baldini, Nicola, Avnet, Sofia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198446/
https://ncbi.nlm.nih.gov/pubmed/34071200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115760
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