Whole Exome Sequencing of Biliary Tubulopapillary Neoplasms Reveals Common Mutations in Chromatin Remodeling Genes

SIMPLE SUMMARY: Intraductal tubulopapillary neoplasms (ITPN) have recently been described as rare precursor lesions of pancreatic ductal adenocarcinoma and cholangiocarcinoma. Despite a high number of associated invasive adenocarcinomas at the time of diagnosis, patients with ITPN tend to have a muc...

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Publicat a:Cancers (Basel)
Autors principals: Gross, Claudia, Engleitner, Thomas, Lange, Sebastian, Weber, Julia, Jesinghaus, Moritz, Konukiewitz, Björn, Muckenhuber, Alexander, Steiger, Katja, Pfarr, Nicole, Goeppert, Benjamin, Keller, Gisela, Weichert, Wilko, Adsay, Nazmi Volkan, Klöppel, Günter, Rad, Roland, Esposito, Irene, Schlitter, Anna Melissa
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198366/
https://ncbi.nlm.nih.gov/pubmed/34205964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112742
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