The Role of Non-Specific Interactions in Canonical and ALT-Associated PML-Bodies Formation and Dynamics

In this work, we put forward a hypothesis about the decisive role of multivalent nonspecific interactions in the early stages of PML body formation. Our analysis of the PML isoform sequences showed that some of the PML isoforms, primarily PML-II, are prone to phase separation due to their polyamphol...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fonin, Alexander V., Silonov, Sergey A., Shpironok, Olesya G., Antifeeva, Iuliia A., Petukhov, Alexey V., Romanovich, Anna E., Kuznetsova, Irina M., Uversky, Vladimir N., Turoverov, Konstantin K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198325/
https://ncbi.nlm.nih.gov/pubmed/34072343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115821
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