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Challenging Safety and Efficacy of Retinal Gene Therapies by Retinogenesis
Gene-expression programs modulated by transcription factors (TFs) mediate key developmental events. Here, we show that the synthetic transcriptional repressor (TR; ZF6-DB), designed to treat Rhodopsin-mediated autosomal dominant retinitis pigmentosa (RHO-adRP), does not perturb murine retinal develo...
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| Yayımlandı: | Int J Mol Sci |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8198227/ https://ncbi.nlm.nih.gov/pubmed/34071252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115767 |
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