Transcriptomic Profiling of the Liver Sinusoidal Endothelium during Cirrhosis Reveals Stage-Specific Secretory Signature

SIMPLE SUMMARY: We define the transcriptome and secretome of primary LSECs during the progression of cirrhosis, revealing specific molecular signatures, novel biomarkers and therapeutic targets for new disease-modifying treatments for patients with advanced chronic liver disease. ABSTRACT: The poor...

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Udgivet i:Cancers (Basel)
Main Authors: Manicardi, Nicolò, Fernández-Iglesias, Anabel, Abad-Jordà, Laia, Royo, Felix, Azkargorta, Mikel, Ortega-Ribera, Martí, Sanfeliu-Redondo, David, Martínez-Alcocer, Ana, Elortza, Felix, Hessheimer, Amelia J., Fondevila, Constantino, Lozano, Juan José, García-Pagán, Juan Carlos, Bosch, Jaime, Cubero, Francisco Javier, Albillos, Agustín, Vaquero, Javier, Falcón-Pérez, Juan M., Gracia-Sancho, Jordi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198220/
https://ncbi.nlm.nih.gov/pubmed/34072510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112688
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