Nicotinamide N-Methyltransferase in Acquisition of Stem Cell Properties and Therapy Resistance in Cancer

The activity of nicotinamide N-methyltransferase (NNMT) is tightly linked to the maintenance of the nicotinamide adenine dinucleotide (NAD(+)) level. This enzyme catalyzes methylation of nicotinamide (NAM) into methyl nicotinamide (MNAM), which is either excreted or further metabolized to N1-methyl-...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Novak Kujundžić, Renata, Prpić, Marin, Đaković, Nikola, Dabelić, Nina, Tomljanović, Marko, Mojzeš, Anamarija, Fröbe, Ana, Trošelj, Koraljka Gall
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197977/
https://ncbi.nlm.nih.gov/pubmed/34073600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115681
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