Ca(2+) overload- and ROS-associated mitochondrial dysfunction contributes to δ-tocotrienol-mediated paraptosis in melanoma cells

ABSTRACT: Melanoma is an aggressive tumor with still poor therapy outcomes. δ-tocotrienol (δ-TT) is a vitamin E derivative displaying potent anti-cancer properties. Previously, we demonstrated that δ-TT triggers apoptosis in human melanoma cells. Here, we investigated whether it might also activate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Apoptosis
Main Authors: Raimondi, Michela, Fontana, Fabrizio, Marzagalli, Monica, Audano, Matteo, Beretta, Giangiacomo, Procacci, Patrizia, Sartori, Patrizia, Mitro, Nico, Limonta, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197726/
https://ncbi.nlm.nih.gov/pubmed/33811561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-021-01668-y
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados