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The association of DAT gene methylation with striatal DAT availability in healthy subjects

BACKGROUND: DNA methylation inhibits gene expression by preventing transcription factors from binding to DNA. Functioning of nigrostriatal dopaminergic neurons is influenced by the expression of the dopamine transporter (DAT), and genetic variations in the gene encoding DAT contribute to differences...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Pak, Kyoungjune, Seok, Ju Won, Nam, Hyun-Yeol, Seo, Seongho, Lee, Myung Jun, Kim, Keunyoung, Kim, In Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197693/
https://ncbi.nlm.nih.gov/pubmed/34120227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-021-00800-y
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