The DEAD/DEAH Box Helicase, DDX11, Is Essential for the Survival of Advanced Clear Cell Renal Cell Carcinoma and Is a Determinant of PARP Inhibitor Sensitivity

SIMPLE SUMMARY: DDX11, a helicase involved in sister chromatid cohesion, was identified as a significant biomarker of aggressive renal cell carcinoma (RCC) in our previous studies. In this study, we evaluated the molecular pathways through which DDX11 is involved in RCC cell survival. Furthermore, w...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Park, Jee Soo, Lee, Myung Eun, Jang, Won Sik, Rha, Koon Ho, Lee, Seung Hwan, Lee, Jongsoo, Ham, Won Sik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8197413/
https://ncbi.nlm.nih.gov/pubmed/34073906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112574
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