High Serum PD-L1 Levels Are Associated with Poor Survival in Urothelial Cancer Patients Treated with Chemotherapy and Immune Checkpoint Inhibitor Therapy

SIMPLE SUMMARY: Advanced urothelial bladder cancer (BC) shows a heterogeneous response to both platinum and immune checkpoint inhibitor (ICI) therapies. The PD-1/PD-L1 signaling pathway represents an immune escape mechanism and tissue PD-L1 expression was shown to be associated with patients’ progno...

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Publicat a:Cancers (Basel)
Autors principals: Krafft, Ulrich, Olah, Csilla, Reis, Henning, Kesch, Claudia, Darr, Christopher, Grünwald, Viktor, Tschirdewahn, Stephan, Hadaschik, Boris, Horvath, Orsolya, Kenessey, Istvan, Nyirady, Peter, Varadi, Melinda, Modos, Orsolya, Csizmarik, Anita, Szarvas, Tibor
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196869/
https://ncbi.nlm.nih.gov/pubmed/34067347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13112548
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