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Exposure to the Methylselenol Precursor Dimethyldiselenide Induces a Reductive Endoplasmic Reticulum Stress in Saccharomyces cerevisiae

Methylselenol (MeSeH) is a major cytotoxic metabolite of selenium, causing apoptosis in cancer cells through mechanisms that remain to be fully established. Previously, we demonstrated that, in Saccharomyces cerevisiae, MeSeH toxicity was mediated by its metabolization into selenomethionine by O-ace...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Dauplais, Marc, Mahou, Pierre, Plateau, Pierre, Lazard, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196827/
https://ncbi.nlm.nih.gov/pubmed/34067304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115467
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