D-dopachrome tautomerase activates COX2/PGE(2) pathway of astrocytes to mediate inflammation following spinal cord injury

BACKGROUND: Astrocytes are the predominant glial cell type in the central nervous system (CNS) that can secrete various cytokines and chemokines mediating neuropathology in response to danger signals. D-dopachrome tautomerase (D-DT), a newly described cytokine and a close homolog of macrophage migra...

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Publicat a:J Neuroinflammation
Autors principals: Ji, Huiyuan, Zhang, Yuxin, Chen, Chen, Li, Hui, He, Bingqiang, Yang, Ting, Sun, Chunshuai, Hao, Huifei, Zhang, Xingyuan, Wang, Yingjie, Zhou, Yue, Zhu, Zhenjie, Hu, Yuming, Li, Aihong, Guo, Aisong, Wang, Yongjun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196514/
https://ncbi.nlm.nih.gov/pubmed/34116703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02186-z
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