Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis

BACKGROUND: An increasing number of studies evidences that amyotrophic lateral sclerosis (ALS) is characterized by extensive alterations in different cell types and in different regions besides the CNS. We previously reported the upregulation in ALS models of a gene called fibroblast-specific protei...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Milani, Martina, Mammarella, Eleonora, Rossi, Simona, Miele, Chiara, Lattante, Serena, Sabatelli, Mario, Cozzolino, Mauro, D’Ambrosi, Nadia, Apolloni, Savina
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196441/
https://ncbi.nlm.nih.gov/pubmed/34118929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02184-1
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