Targeting S100A4 with niclosamide attenuates inflammatory and profibrotic pathways in models of amyotrophic lateral sclerosis

BACKGROUND: An increasing number of studies evidences that amyotrophic lateral sclerosis (ALS) is characterized by extensive alterations in different cell types and in different regions besides the CNS. We previously reported the upregulation in ALS models of a gene called fibroblast-specific protei...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Milani, Martina, Mammarella, Eleonora, Rossi, Simona, Miele, Chiara, Lattante, Serena, Sabatelli, Mario, Cozzolino, Mauro, D’Ambrosi, Nadia, Apolloni, Savina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196441/
https://ncbi.nlm.nih.gov/pubmed/34118929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02184-1
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