Development of a capture sequencing assay for enhanced detection and genotyping of tick-borne pathogens

Inadequate sensitivity has been the primary limitation for implementing high-throughput sequencing for studies of tick-borne agents. Here we describe the development of TBDCapSeq, a sequencing assay that uses hybridization capture probes that cover the complete genomes of the eleven most common tick...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Jain, Komal, Tagliafierro, Teresa, Marques, Adriana, Sanchez-Vicente, Santiago, Gokden, Alper, Fallon, Brian, Mishra, Nischay, Briese, Thomas, Kapoor, Vishal, Sameroff, Stephen, Guo, Cheng, Marcos, Luis A., Hu, Linden, Lipkin, W. Ian, Tokarz, Rafal
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196166/
https://ncbi.nlm.nih.gov/pubmed/34117323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91956-z
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