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A Review of Specific Biomarkers of Chronic Renal Injury and Their Potential Application in Nonclinical Safety Assessment Studies

A host of novel renal biomarkers have been developed over the past few decades which have enhanced monitoring of renal disease and drug-induced kidney injury in both preclinical studies and in humans. Since chronic kidney disease (CKD) and acute kidney injury (AKI) share similar underlying mechanism...

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Vydáno v:Toxicol Pathol
Hlavní autoři: Obert, Leslie A., Elmore, Susan A., Ennulat, Daniela, Frazier, Kendall S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195817/
https://ncbi.nlm.nih.gov/pubmed/33576319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623320985045
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