Polarized endosome dynamics engage cytoplasmic Par-3 that recruits dynein during asymmetric cell division

In the developing embryos, the cortical polarity regulator Par-3 is critical for establishing Notch signaling asymmetry between daughter cells during asymmetric cell division (ACD). How cortically localized Par-3 establishes asymmetric Notch activity in the nucleus is not understood. Here, using in...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Zhao, Xiang, Garcia, Jason Q., Tong, Kai, Chen, Xingye, Yang, Bin, Li, Qi, Dai, Zhipeng, Shi, Xiaoyu, Seiple, Ian B., Huang, Bo, Guo, Su
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2021
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195473/
https://ncbi.nlm.nih.gov/pubmed/34117063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg1244
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