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Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

BACKGROUND: Helminths can modulate the host immune response to Plasmodium falciparum and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria vaccine candidate, a recombinant protein consisti...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Nouatin, Odilon, Mengue, Juliana Boex, Dejon-Agobé, Jean Claude, Fendel, Rolf, Ibáñez, Javier, Ngoa, Ulysse Ateba, Edoa, Jean Ronald, Adégbité, Bayodé Roméo, Honkpéhédji, Yabo Josiane, Zinsou, Jeannot Fréjus, Hounkpatin, Aurore Bouyoukou, Moutairou, Kabirou, Homoet, Andreas, Esen, Meral, Kreidenweiss, Andrea, Hoffman, Stephen L., Theisen, Michael, Luty, Adrian J. F., Lell, Bertrand, Agnandji, Selidji Todagbe, Mombo-Ngoma, Ghyslain, Ramharter, Michael, Kremsner, Peter, Mordmüller, Benjamin, Adegnika, Ayôla Akim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195366/
https://ncbi.nlm.nih.gov/pubmed/34061838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009361
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