High-throughput framework for genetic analyses of adverse drug reactions using electronic health records

Understanding the contribution of genetic variation to drug response can improve the delivery of precision medicine. However, genome-wide association studies (GWAS) for drug response are uncommon and are often hindered by small sample sizes. We present a high-throughput framework to efficiently iden...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Zheng, Neil S., Stone, Cosby A., Jiang, Lan, Shaffer, Christian M., Kerchberger, V. Eric, Chung, Cecilia P., Feng, QiPing, Cox, Nancy J., Stein, C. Michael, Roden, Dan M., Denny, Joshua C., Phillips, Elizabeth J., Wei, Wei-Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195357/
https://ncbi.nlm.nih.gov/pubmed/34061827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009593
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