A Drug Repositioning Approach Identifies a Combination of Compounds as a Potential Regimen for Chronic Lymphocytic Leukemia Treatment

Drug repositioning is a promising and powerful innovative strategy in the field of drug discovery. In this study, we screened a compound-library containing 800 Food and Drug Administration approved drugs for their anti-leukemic effect. All screening activities made use of human peripheral blood mono...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Nehdi, Atef, Samman, Nosaibah, Mashhour, Abdullah, Alhallaj, Alshaimaa, Trivilegio, Thadeo, Gul, Sheraz, Reinshagen, Jeanette, Alaskar, Ahmed, Gmati, Gamal, Abuelgasim, Khadega A., Mansour, Fatmah, Boudjelal, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195271/
https://ncbi.nlm.nih.gov/pubmed/34123769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.579488
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