Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease

BACKGROUND: Most congenital heart defects (CHDs) result from complex interactions among genetic susceptibilities, epigenetic modifications, and maternal environmental exposures. Characterizing the complex relationship between genetic, epigenetic, and transcriptomic variation will enhance our underst...

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Pubblicato in:BMC Genom Data
Autori principali: Li, Ming, Lyu, Chen, Huang, Manyan, Do, Catherine, Tycko, Benjamin, Lupo, Philip J., MacLeod, Stewart L., Randolph, Christopher E., Liu, Nianjun, Witte, John S., Hobbs, Charlotte A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8194170/
https://ncbi.nlm.nih.gov/pubmed/34112112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-021-00975-2
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