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Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging

The antidepressant drug amitriptyline is used in the treatment of clinical depression and a variety of neurological conditions such as anxiety, neuropathic pain disorders and migraine. Antidepressants are associated with both therapeutic and untoward effects, and their use in the elderly has tripled...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Bang, Eunyoung, Tobery, Angelika, Montgomery, Karienn S., Fincher, Annette S., Earnest, David J., Murchison, David A., Griffith, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193944/
https://ncbi.nlm.nih.gov/pubmed/34122049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.673155
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