An in vitro Perfused Macroencapsulation Device to Study Hemocompatibility and Survival of Islet-Like Cell Clusters

Transplantation of hydrogel-encapsulated pancreatic islets is a promising long-term treatment for type 1 diabetes that restores blood glucose regulation while providing graft immunoprotection. Most human-scale islet encapsulation devices that rely solely on diffusion fail to provide sufficient surfa...

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Bibliographic Details
Published in:Front Bioeng Biotechnol
Main Authors: Fernandez, Stephanie A., Danielczak, Lisa, Gauvin-Rossignol, Gabrielle, Hasilo, Craig, Bégin-Drolet, André, Ruel, Jean, Paraskevas, Steven, Leask, Richard L., Hoesli, Corinne A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Bioengineering and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193939/
https://ncbi.nlm.nih.gov/pubmed/34124024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.674125
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