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SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats

BACKGROUND: How to obtain a small interfering RNA (siRNA) vector has become a moot point in recent years. Exosomes (Exo) show advantages of long survival time in vivo, high transmission efficiency, and easy penetration across the blood-spinal cord barrier, renowned as excellent carriers of bioactive...

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Podrobná bibliografie
Vydáno v:Stem Cell Res Ther
Hlavní autoři: Huang, Wei, Qu, Mingjia, Li, Lu, Liu, Tao, Lin, Miaoman, Yu, Xiaobing
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193895/
https://ncbi.nlm.nih.gov/pubmed/34112262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02401-x
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