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Applications of CRISPR Genome Editing to Advance the Next Generation of Adoptive Cell Therapies for Cancer
Adoptive cell therapy (ACT) for cancer shows tremendous potential, however, several challenges preclude its widespread use. These include poor T cell function in hostile tumor microenvironments, a lack of tumor-specific target antigens, and the high cost and poor scalability of cell therapy manufact...
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| Vydáno v: | Cancer Discov |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8193798/ https://ncbi.nlm.nih.gov/pubmed/33563662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-1083 |
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