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Suppressed estrogen supply via extra-ovarian progesterone receptor membrane component 1 in menopause

In post-menopausal women, intra-mammary estrogen, which is converted from extra-ovarian estrone (E1), promotes the growth of breast cancer. Since the aromatase inhibitor letrozole does not suppress 17β-estradiol (E2) production from E1, high intra-mammary E1 concentrations impair letrozole's th...

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Detalhes bibliográficos
Publicado no:J Biomed Res
Main Authors: Lee, Sang R., Yang, Hyun, Jo, Seong Lae, Lee, Young Ho, Lee, Hye Won, Park, Bae-keun, Hong, Eui-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193715/
https://ncbi.nlm.nih.gov/pubmed/33911053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.35.20200172
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