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Remodeling of the tumor microenvironment using an engineered oncolytic vaccinia virus improves PD-L1 inhibition outcomes

Immune checkpoint inhibitor (ICI) immunotherapies have vastly improved therapeutic outcomes for patients with certain cancer types, but these responses only manifest in a small percentage of all cancer patients. The goal of the present study was to improve checkpoint therapy efficacy by utilizing an...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Lou, Jiaying, Dong, Jialin, Xu, Ruijun, Zeng, Hui, Fang, Lijuan, Wu, Yi, Liu, Yang, Wang, Shibing
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193643/
https://ncbi.nlm.nih.gov/pubmed/34060602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20204186
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