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Drug crystal growth in ternary amorphous solid dispersions: Effect of surfactants and polymeric matrix-carriers

The present study evaluates the crystal growth rate of amorphous drugs when dispersed in different ternary polymeric amorphous solid dispersions (ASDs) in the presence of surfactants. Specifically, ternary ASDs of aprepitant (APT, selected as a model drug) were prepared via melt-quench cooling by ev...

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Bibliografische gegevens
Gepubliceerd in:Int J Pharm X
Hoofdauteurs: Kapourani, Afroditi, Tzakri, Theodora, Valkanioti, Vasiliki, Kontogiannopoulos, Konstantinos N., Barmpalexis, Panagiotis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193146/
https://ncbi.nlm.nih.gov/pubmed/34151251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2021.100086
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