Novel 1,2,4-oxadiazole derivatives as selective butyrylcholinesterase inhibitors: Design, synthesis and biological evaluation

Alzheimer's disease (AD) is a progressive mental disorder that brings a huge economic burden to the healthcare systems. During this illness, acetylcholine levels in the cholinergic systems gradually diminish, which results in severe memory loss and cognitive impairments. Moreover, Butyrylcholin...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Nazari, Maryam, Rezaee, Elham, Hariri, Roshanak, Akbarzadeh, Tahmineh, Tabatabai, Sayyed Abbas
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192883/
https://ncbi.nlm.nih.gov/pubmed/34121977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2021-3569
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