Inhibition of angiotensin II type 1 receptor by candesartan reduces tumor growth and ameliorates fibrosis in colorectal cancer

Colorectal cancer (CRC) is an important cause of cancer-related mortality. Aberrant activation of the renin-angiotensin system (RAS) is reported to be associated with poor clinical outcomes in patients with CRC. This study was designed to explore the anti-tumor effects of the angiotensin receptor bl...

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Publicado en:EXCLI J
Autores principales: Tabatabai, Ehsan, Khazaei, Majid, Asgharzadeh, Fereshteh, Nazari, Seyedeh Elnaz, Shakour, Neda, Fiuji, Hamid, Ziaeemehr, Aghigh, Mostafapour, Asma, Parizadeh, Mohammad Reza, Nouri, Mohammad, Hassanian, Seyed Mahdi, Hadizadeh, Farzin, Ferns, Gordon A, Rahmati, Mohammad, Rahmani, Farzad, Avan, Amir
Formato: Artigo
Lenguaje:Inglês
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2021
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192880/
https://ncbi.nlm.nih.gov/pubmed/34121975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2021-3421
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