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Asymmetric benzylic C(sp(3))−H acylation via dual nickel and photoredox catalysis

Asymmetric C(sp(3))−H functionalization is a persistent challenge in organic synthesis. Here, we report an asymmetric benzylic C−H acylation of alkylarenes employing carboxylic acids as acyl surrogates for the synthesis of α-aryl ketones via nickel and photoredox dual catalysis. This mild yet straig...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Huan, Leitao, Shu, Xiaomin, Zu, Weisai, Zhong, De, Huo, Haohua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192574/
https://ncbi.nlm.nih.gov/pubmed/34112783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23887-2
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