Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

Tissue macrophages self-renew during homeostasis and produce inflammatory mediators upon microbial infection. We examined the relationship between proliferative and inflammatory properties of tissue macrophages by defining the impact of the Wnt/β-catenin pathway, a central regulator of self-renewal,...

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Vydáno v:Immunity
Hlavní autoři: Zhu, Bibo, Wu, Yue, Huang, Su, Zhang, Ruixuan, Son, Young Min, Li, Chaofan, Cheon, In Su, Gao, Xiaochen, Wang, Min, Chen, Yao, Zhou, Xian, Nguyen, Quynh, Phan, Anthony T., Behl, Supriya, Taketo, M. Mark, Mack, Matthias, Shapiro, Virginia S., Zeng, Hu, Ebihara, Hideki, Mullon, John J., Edell, Eric S., Reisenauer, Janani S., Demirel, Nadir, Kern, Ryan M., Chakraborty, Rana, Cui, Weiguo, Kaplan, Mark H., Zhou, Xiaobo, Goldrath, Ananda W., Sun, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192557/
https://ncbi.nlm.nih.gov/pubmed/33951416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.04.001
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