Unravelling the mechanisms of Type 1A topoisomerases using single-molecule approaches

Topoisomerases are essential enzymes that regulate DNA topology. Type 1A family topoisomerases are found in nearly all living organisms and are unique in that they require single-stranded (ss)DNA for activity. These enzymes are vital for maintaining supercoiling homeostasis and resolving DNA entangl...

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Gardado en:
Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Spakman, Dian, Bakx, Julia A M, Biebricher, Andreas S, Peterman, Erwin J G, Wuite, Gijs J L, King, Graeme A
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2021
Assuntos:
Survey and Summary
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191776/
https://ncbi.nlm.nih.gov/pubmed/33963870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab239
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