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Cx43 phosphorylation sites regulate pancreatic cancer metastasis

Pancreatic ductal adenocarcinoma (PDA) is aggressive, highly metastatic and characterized by a robust desmoplasia. Connexin proteins that form gap junctions have been implicated in tumor suppression for over 30 years. Cx43, the most widely expressed connexin, regulates cell behaviors, including migr...

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Foilsithe in:Oncogene
Main Authors: Solan, Joell L., Hingorani, Sunil R., Lampe, Paul D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191514/
https://ncbi.nlm.nih.gov/pubmed/33603164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01668-x
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