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Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs

The adhesion G protein–coupled receptor CD97 and its ligand complement decay-accelerating factor CD55 are important binding partners in the human immune system. Dysfunction in this binding has been linked to immune disorders such as multiple sclerosis and rheumatoid arthritis, as well as various can...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Niu, Minghui, Xu, Shengzhao, Yang, Jie, Yao, Deqiang, Li, Na, Yan, Jie, Zhong, Guisheng, Song, Gaojie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191316/
https://ncbi.nlm.nih.gov/pubmed/33992645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100776
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