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Neuronal Pentraxin 1 Promotes Hypoxic-Ischemic Neuronal Injury by Impairing Mitochondrial Biogenesis via Interactions With Active Bax[6A7] and Mitochondrial Hexokinase II

Mitochondrial dysfunction is a key mechanism of cell death in hypoxic-ischemic brain injury. Neuronal pentraxin 1 (NP1) has been shown to play crucial roles in mitochondria-mediated neuronal death. However, the underlying mechanism(s) of NP1-induced mitochondrial dysfunction in hypoxia-ischemia (HI)...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ASN Neuro
Main Authors: Al Rahim, Md, Thatipamula, Shabarish, Pasinetti, Giulio M., Hossain, Mir Ahamed
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191073/
https://ncbi.nlm.nih.gov/pubmed/34098747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/17590914211012888
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