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Specific detection of high mobility group box 1 degradation product with a novel ELISA

BACKGROUND: During sepsis or sterile tissue injury, the nuclear protein high mobility group box 1 (HMGB1) can be released to the extracellular space and ultimately into systemic circulation, where it mediates systemic inflammation and remote organ failure. The proinflammatory effects of HMGB1 can be...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Totoki, Takaaki, Ito, Takashi, Yamada, Shingo, Honda, Goichi, Hattori, Tsuyoshi, Maruyama, Ikuro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190996/
https://ncbi.nlm.nih.gov/pubmed/34107884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-021-00323-1
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