Association of Novel Locus With Rheumatic Heart Disease in Black African Individuals: Findings From the RHDGen Study

IMPORTANCE: Rheumatic heart disease (RHD), a sequela of rheumatic fever characterized by permanent heart valve damage, is the leading cause of cardiac surgery in Africa. However, its pathophysiologic characteristics and genetics are poorly understood. Understanding genetic susceptibility may aid in...

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Bibliographic Details
Published in:JAMA Cardiol
Main Authors: Machipisa, Tafadzwa, Chong, Michael, Muhamed, Babu, Chishala, Chishala, Shaboodien, Gasnat, Pandie, Shahiemah, de Vries, Jantina, Laing, Nakita, Joachim, Alexia, Daniels, Rezeen, Ntsekhe, Mpiko, Hugo-Hamman, Christopher T., Gitura, Bernard, Ogendo, Stephen, Lwabi, Peter, Okello, Emmy, Damasceno, Albertino, Novela, Celia, Mocumbi, Ana O., Madeira, Goeffrey, Musuku, John, Mtaja, Agnes, ElSayed, Ahmed, Elhassan, Huda H. M., Bode-Thomas, Fidelia, Okeahialam, Basil N., Zühlke, Liesl J., Mulder, Nicola, Ramesar, Raj, Lesosky, Maia, Parks, Tom, Cordell, Heather J., Keavney, Bernard, Engel, Mark E., Paré, Guillaume
Format: Artigo
Language:Inglês
Published: American Medical Association 2021
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Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190704/
https://ncbi.nlm.nih.gov/pubmed/34106200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2021.1627
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