High-intensity exercise training induces mitonuclear imbalance and activates the mitochondrial unfolded protein response in the skeletal muscle of aged mice

The impairment of mitochondrial metabolism is a hallmark of aging. Mitonuclear imbalance and the mitochondrial unfolded protein response (UPRmt) are two conserved mitochondrial mechanisms that play critical roles in ensuring mitochondrial proteostasis and function. Here, we combined bioinformatics,...

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Udgivet i:GeroScience
Main Authors: Cordeiro, André Victor, Peruca, Guilherme Francisco, Braga, Renata Rosseto, Brícola, Rafael Santos, Lenhare, Luciene, Silva, Vagner Ramon Rodrigues, Anaruma, Chadi Pellegrini, Katashima, Carlos Kiyoshi, Crisol, Barbara Moreira, Barbosa, Lucas Torres, Simabuco, Fernando Moreira, da Silva, Adelino Sanchez Ramos, Cintra, Dennys Esper, de Moura, Leandro Pereira, Pauli, José Rodrigo, Ropelle, Eduardo Rochete
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190321/
https://ncbi.nlm.nih.gov/pubmed/32737758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00246-5
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