High-intensity exercise training induces mitonuclear imbalance and activates the mitochondrial unfolded protein response in the skeletal muscle of aged mice

The impairment of mitochondrial metabolism is a hallmark of aging. Mitonuclear imbalance and the mitochondrial unfolded protein response (UPRmt) are two conserved mitochondrial mechanisms that play critical roles in ensuring mitochondrial proteostasis and function. Here, we combined bioinformatics,...

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Vydáno v:GeroScience
Hlavní autoři: Cordeiro, André Victor, Peruca, Guilherme Francisco, Braga, Renata Rosseto, Brícola, Rafael Santos, Lenhare, Luciene, Silva, Vagner Ramon Rodrigues, Anaruma, Chadi Pellegrini, Katashima, Carlos Kiyoshi, Crisol, Barbara Moreira, Barbosa, Lucas Torres, Simabuco, Fernando Moreira, da Silva, Adelino Sanchez Ramos, Cintra, Dennys Esper, de Moura, Leandro Pereira, Pauli, José Rodrigo, Ropelle, Eduardo Rochete
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190321/
https://ncbi.nlm.nih.gov/pubmed/32737758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00246-5
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