Beta-guanidinopropionic acid has age-specific effects on markers of health and function in mice

AMP-activated protein kinase (AMPK) is a central regulator of both lifespan and health across multiple model organisms. β-Guanidinopropionic acid (GPA) is an endogenous AMPK activator previously shown to improve metabolic function in young and obese mice. In this study, we tested whether age of admi...

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Bibliografske podrobnosti
izdano v:GeroScience
Main Authors: Dorigatti, Jonathan D., Thyne, Kevin M., Ginsburg, Brett C., Salmon, Adam B.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2021
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190243/
https://ncbi.nlm.nih.gov/pubmed/33890206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-021-00372-8
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