Endothelin B receptor dysfunction mediates elevated myogenic tone in cerebral arteries from aged male Fischer 344 rats

The human brain requires adequate cerebral blood flow to meet the high demand for nutrients and to clear waste products. With age, there is a chronic reduction in cerebral blood flow in small resistance arteries that can eventually limit proper brain function. The endothelin system is a key mediator...

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Udgivet i:GeroScience
Main Authors: Young, Alexander P., Zhu, Jiequan, Bagher, Amina M., Denovan-Wright, Eileen M., Howlett, Susan E., Kelly, Melanie E.M.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2021
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190196/
https://ncbi.nlm.nih.gov/pubmed/33403617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00309-7
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