Apoptotic mesenchymal stromal cells support osteoclastogenesis while inhibiting multinucleated giant cells formation in vitro

In bone regeneration induced by the combination of mesenchymal stromal cells (MSCs) and calcium-phosphate (CaP) materials, osteoclasts emerge as a pivotal cell linking inflammation and bone formation. Favorable outcomes are observed despite short-term engraftments of implanted MSCs, highlighting the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Humbert, Paul, Brennan, Meadhbh Á., De Lima, Julien, Brion, Régis, Adrait, Annie, Charrier, Céline, Brulin, Bénédicte, Trichet, Valérie, Couté, Yohann, Blanchard, Frédéric, Layrolle, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190145/
https://ncbi.nlm.nih.gov/pubmed/34108508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91258-4
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