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Simple and versatile imaging of genomic loci in live mammalian cells and early pre-implantation embryos using CAS-LiveFISH

Visualizing the 4D genome in live cells is essential for understanding its regulation. Programmable DNA-binding probes, such as fluorescent clustered regularly interspaced short palindromic repeats (CRISPR) and transcription activator-like effector (TALE) proteins have recently emerged as powerful t...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Geng, Yongtao, Pertsinidis, Alexandros
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190065/
https://ncbi.nlm.nih.gov/pubmed/34108610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91787-y
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